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CRAFTMOL investigates novel chemical transformations to create diverse molecular architectures, focusing on polyene cyclizations. The project aims to develop new synthetic pathways for producing bioactive natural products with potential therapeutic applications.
Polyene cyclizations belong to the most powerful and fascinating chemical transformations to rapidly assemble molecular architectures.
However, the very limited substitution pattern of known substrates and natures inability to accommodate heteroatoms or substituents other than methyl restrict molecular diversity, complexity and functionality. CRAFTMOL addresses these limitations by investigating a set of novel heteroatom-substituted and tri/tetrasubstituted polyenes.
The participation of these s…
UNIVERSITAET INNSBRUCK
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