CORDIS Project
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This project investigates the genetic factors contributing to colorectal cancer risk by exploring molecular pathways linked to specific genetic variations. It aims to develop predictive assays using tissue samples to identify individuals at higher risk for the disease.
Colorectal cancer (CRC) is one of the most common cancers in both men and women in the EU.
Recent advances in CRC genetics, largely through genome-wide association studies (GWAS), have identified 17 common polymorphisms (SNPs) associated with increased CRC risk in the general population.
The SNPs only account for a minority of the genetic variation in CRC and genotyping these SNPs alone is not a sufficiently powerful risk predictor to be used in clinical practice.
However, whilst the nature of t…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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