CORDIS Project
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This project investigates the structure of sperm cell centrioles using advanced imaging techniques. By understanding their ultrastructure, the research aims to clarify their role in fertilization and improve insights into male infertility, which is a significant factor in assisted reproductive technology.
Applying cutting-edge technology like cryo-electron tomography, subtomogram averaging and single-particle cryo-electron microscopy to sperm cells, I aim to uncover structural details of sperm centrioles.As most other cells in the human body, sperm cells carry two centrioles called the proximal and the distal centriole.
In the field of reproduction biology, it is widely accepted that these organelles are essential for the process of fertilization.
One of their many important functions for this pr…
UNIVERSITEIT UTRECHT
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