CORDIS Project
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This project focuses on developing advanced tools for genetic modifications of gut bacteria using bacteriophage delivery systems and CRISPR-Cas technology. The goal is to enhance our understanding of the gut microbiome and create targeted therapies for health improvement.
Humans live in a symbiotic relationship with trillions of microorganisms that inhabit our bodies and play an important role in health and disease.
There is a growing interest in manipulating the microbiome to improve health, yet we currently lack the knowledge and technology to carry out precise interventions.
The objective of this proposal is to enable efficient in situ genetic perturbations of bacteria in the gut environment by developing the next generation of synthetic biology tools based on…
INSTITUT PASTEUR
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