CORDIS Project
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This project explores the role of CRISPR-Cas systems in microbial immunity and genetic diversity. It investigates how these systems affect gene transfer and diversity within populations, aiming to uncover their ecological and evolutionary significance beyond viral defense.
CRISPR-Cas systems are microbial defense systems that provide prokaryotes with acquired and heritable DNA-based immunity against selfish genetic elements, primarily viruses.
However, the full scope of benefits that these systems can provide, as well as their costs remain unknown.
Specifically, it is unclear whether the benefits against viral infection outweigh the continual costs incurred even in the absence of parasitic elements, and whether CRISPR-Cas systems affect microbial genome diversity…
TEL AVIV UNIVERSITY
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