CORDIS Project
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CryoCLEMAV focuses on understanding adenovirus disassembly and entry mechanisms using advanced microscopy techniques. By combining virology with cryo-electron microscopy, the project aims to achieve unprecedented insights into virus behavior at a cellular level, contributing to the development of therapeutic tools.
Adenoviruses (AdVs) are very contagious viruses widespread in vertebrated.
Human AdVs infections mainly affect children and immune-supressed people.
On the other hand, AdV-derived vectors, nanocarriers and vaccines have turn out to be efficient therapeutic tools.
Understanding AdVs disassembly mechanisms is vital to advance research in antiviral drugs, gene therapies, nanocarriers and vaccines.
AdV particles’ metastability is key for surviving environmental conditions and cell defences, but at t…
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
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