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CryoLipNano focuses on improving the delivery of RNA therapeutics using Lipid Nanoparticles (LNPs). The project aims to enhance understanding of LNP structure and dynamics to develop more effective gene delivery systems for medical applications.
RNA therapeutics are revolutionizing medicine, offering new treatment possibilities for diseases once considered undruggable.
Central to the delivery of nucleic acids, especially mRNA, is the use of Lipid Nanoparticles (LNPs) – the most advanced and the only clinically approved gene delivery platform. LNPs protect mRNA from degradation, facilitate its transfer, and ensure delivery into the cell.
Despite their potential, the therapeutic potency of RNA-LNPs remains limited due to suboptimal RNA de…
NATIONAL HELLENIC RESEARCH FOUNDATION EIE NHRF
ETHNIKO IDRYMA EREVNON
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