CORDIS Project
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This project focuses on developing a new method for forming carbon-nitrogen bonds, essential for creating drugs and agrochemicals. It utilizes a radical reactivity approach to enable direct substitution reactions between nitrogen-containing molecules and alkyl halides, aiming to simplify complex chemical processes.
The formation of carbon–nitrogen bonds is crucial to the preparation of molecules that impact almost every aspects of our lives like drugs, agrochemicals and food additives.In text-books, creating C–N bonds is approached considering the natural nucleophilic character of N-molecules in substitution reactions with alkyl halides.
In practice, these reactions are only used in the case of highly reactive substrates with low steric hinderance (e.g. primary amines + primary alkyl halides).
The vast maj…
THE UNIVERSITY OF MANCHESTER
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