CORDIS Project
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This project aims to engineer Cutibacterium acnes to produce antimicrobial peptides for treating skin infections caused by Staphylococcus aureus. By utilizing a novel plasmid system, it seeks to limit antibiotic resistance and enhance the efficacy of topical treatments.
Our skin is colonized by a myriad of bacteria, fungi and viruses that are collectively called the skin microbiota.
The most common and consequential bacterial skin pathogen in humans is Staphylococcus aureus.
It is an invasive pathogen responsible for varied ailments that commonly evolves resistance to antibiotics.
Antimicrobial peptides (AMPs) have drawn interest from the scientific community because they are less prone to resistance development.
However, they typically require complex formulat…
UNIVERSIDAD POMPEU FABRA
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