CORDIS Project
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This project investigates the mechanisms of cell movement in response to chemical signals, which is essential for processes like immune response and cancer metastasis. By using advanced imaging techniques, it aims to understand how cell polarity is established.
Directed cell movement in a chemical gradient, chemotaxis, is a prerequisite for many vital processes like the immune response and wound healing, but it is also the basis for cancer spreading (metastasis).
It is governed by extracellular gradients of signal molecules.
While the receptors in the cell membrane are mostly identified, it is still unknown how the cell builds up the phenotype with defined front and rear edge required for directed movement In this project two potential ordering paramet…
UNIVERSITEIT LEIDEN
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