CORDIS Project
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This project investigates the mechanisms controlling developmental timing in the roundworm C. elegans. By studying the genetic and environmental factors influencing cyclical timers, it aims to enhance understanding of biological timing mechanisms, which could have implications for stem cell regulation and regenerative…
Organismal development requires proper timing of events such as cell fate choices, but the mechanisms that control temporal patterning remain poorly understood.
In particular, we know little of the cyclical timers, or ‘clocks’, that control recurring events such as vertebrate segmentation or nematode molting.
Furthermore, it is unknown how cyclical timers are coordinated with the global, or linear, timing of development, e.g. to ensure an appropriate number of cyclical repeats.
We propose to elu…
FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION
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