CORDIS Project
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The CycloproBio project investigates cyclopropane synthase enzymes to develop a mild biocatalytic method for cyclopropanation. By characterizing these enzymes and exploring their substrate selectivity, the project aims to enhance the sustainable synthesis of chemicals and pharmaceuticals without relying on hazardous co…
The cyclopropane ring is an important structural motif present in many pharmaceutical compounds and widely used as reactive building blocks in the synthesis of chemicals.
Many synthetic strategies to access cyclopropanes have been developed to date, most of which typically require the use of potentially explosive diazo-carbene compounds as substrates.
Even recently proposed enzymatic transformations, exploiting cytochromes P450 and myoglobin, require the use of stoichiometric carbene co-substrat…
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United Kingdom, London
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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