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The CytoLysoReg project investigates how cytokines regulate lysosomes, which are crucial for cell function and implicated in various diseases. By understanding these molecular mechanisms, the project aims to develop new strategies for treating lysosomal-related diseases such as cancer and lysosomal storage disorders.
Dysfunction of lysosomes—the recycling plants of cells, now recognised to participate in multiple aspects of cell physiology—is involved at the onset of several human diseases.
Importantly, most of the functions carried out by lysosomes depend on hydrolytic activities within their lumen.
Thus, a deeper understanding of the signalling pathways involved in the regulation of lysosomes would provide new tools to ameliorate the symptoms associated with these diseases.
The regulation of lysosomal gene…
UNIVERSIDAD DE SEVILLA
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