CORDIS Project
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This project investigates titanium-based complexes as alternative chemotherapeutic agents to cisplatin, focusing on their stability in water and anti-tumor potency. The research aims to develop formulations and conduct in vivo testing to assess safety and efficacy, paving the way for potential pharmaceutical applicatio…
Cisplatin is a platinum-based complex used widely as a chemotherapeutic drug.
However, due to its limitations, including narrow activity range and severe side effects, other transition metal complexes are investigated as antitumorur agents.
Titanium complexes that previously reached clinical trials showed fair activity, and were mainly limited by rapid decomposition in water, within minutes.
Titanium complexes of diamino bis(phenolato) (""salan"") ligands studied in our laboratory under the ERC…
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