CORDIS Project
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This project develops a multi-organ-on-a-chip device to study type 2 diabetes mechanisms and test new drugs. It integrates engineered muscle tissues and pancreatic islets to analyze glucose metabolism and insulin secretion, aiming to enhance drug discovery processes.
Insulin secretion and insulin action are critical for normal glucose homeostasis.
Defects in both of these processes lead to type 2 diabetes (T2D).
Unravelling the mechanisms that lead to T2D is fundamental in the search of new molecular drugs to prevent and control this disease.
Organ-on-a-chip devices offer new approaches for T2D disease modelling and drug discovery by providing biologically relevant models of tissues and organs in vitro integrated with biosensors.
As such, organ-on-a-chip dev…
FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
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