CORDIS Project
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This project focuses on developing a mathematical model to analyze and predict the movement of proteins, organelles, and DNA within cells. It aims to understand how these components interact with their environment, particularly in the context of gene therapy and cellular responses to DNA damage.
Cytoplasmic motion is a key determinant of organelle transport, protein-protein interactions, RNA transport and drug delivery, to name but a few cellular phenomena.
Nucleic acid trafficking is important in antisense and gene therapy based on viral and synthetic vectors.
This proposal is dedicated to the theoretical study of intracellular transport of proteins, organelles and DNA particles.
We propose to construct a mathematical model to quantify and predict the spatiotemporal dynamics of complex…
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