CORDIS Project
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This research explores how nutrient availability affects immune responses, particularly in dendritic cells and T cells. By developing new technologies to measure nutrient dynamics, it aims to uncover mechanisms that control immune activation, potentially leading to novel therapeutic strategies.
A new immunoregulatory axis has emerged in recent years demonstrating that cellular metabolism is crucial in controlling immune responses.
This regulatory axis is acutely sensitive to nutrients that fuel metabolic pathways and support nutrient sensitive signalling pathways.
My recent research demonstrates that nutrients are dynamically controlled and are not equally available to all immune cells.
The data shows that activated T cells, clustered around a dendritic cell (DC), can consume the avail…
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
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