CORDIS Project
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This project investigates how mechanical properties influence cell behavior in epithelial tissues, focusing on cell extrusion processes that affect tissue integrity and shape. By exploring the interplay between physical forces and cellular dynamics, the research aims to enhance understanding of tissue homeostasis and i…
Epithelia are assemblies of multiple cells whose complex dynamic behavior relies on physical properties including jamming-unjamming mechanisms, active turbulence and active nematic principles.
The homeostasis of epithelia is crucial to maintain barrier function and integrity while epithelial cells are constantly challenged by the environment.
To face these challenges, epithelia are dynamics and have to deal constantly with cell renewal and apoptotic extrusion, whose balance is key for epithelia…
FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
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