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The DECODE project investigates how the complement system affects the neuroprotective properties of mesenchymal stem cells in treating brain inflammation caused by radiotherapy in pediatric brain tumors. The research employs both in vitro and in vivo models to explore potential therapeutic strategies.
The primary objective of this MSCA-PF proposal is to support Dr.
Laura Pérez Alós in becoming an independent investigator by conducting the innovative DECODE project. DECODE aims to explore the role of the complement system in modulating the neuroprotective mechanism of mesenchymal stem cells (MSCs) in radiotherapy-induced brain inflammation (RIBI) in paediatric brain tumours.
Specifically, the project will investigate the role of complement in RIBI using juvenile mice of both sexes, and the int…
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