CORDIS Project
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This project aims to develop Deep Spatial Proteomics, a novel method that links cellular interactions in tissues to functional protein states. By combining advanced imaging and mass spectrometry, it seeks to uncover mechanisms of diseases like cancer and identify potential biomarkers for improved patient treatment outc…
Health and disease states result from dynamic cellular interactions within spatially defined regions in tissues and organs.
In diseases such as cancer, these interactions are often disturbed, but their systematic analysis with respect to their impact on the proteome, a close proxy for cellular function, has so far remained elusive.
To overcome this major bottleneck in molecular biosciences, I propose to develop and apply Deep Spatial Proteomics (DSP), a multimodal strategy, which for the first t…
MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (MDC)
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