CORDIS Project
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This research investigates the mechanisms of memory formation and retrieval in the brain, focusing on dendritic properties across key regions. By using computational models, it aims to elucidate how dendrites contribute to information processing and memory-related dysfunctions, potentially informing new treatments for…
Understanding the rules and mechanisms underlying memory formation, storage and retrieval is a grand challenge in neuroscience.
In light of cumulating evidence regarding non-linear dendritic events (dendritic-spikes, branch strength potentiation, temporal sequence detection etc) together with activity-dependent rewiring of the connection matrix, the classical notion of information storage via Hebbian-like changes in synaptic connections is inadequate.
While more recent plasticity theories consid…
FOUNDATION FOR RESEARCH AND TECHNOLOGYHELLAS
IDRYMA TECHNOLOGIAS KAI EREVNAS
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