CORDIS Project
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This project investigates the complex relationship between intestinal bacteria and host health, focusing on how immune responses can both tolerate and react to these microbes. It examines the role of dendritic cells and epithelial factors in maintaining immune balance, and the potential consequences of disruptions, inc…
The bacterial microflora has always been regarded as beneficial for the host but recent studies have shown that this symbiosis has risks as well as benefits.
Although active mechanisms allow tolerating the commensal flora, the physiological stress that is associated with the symbionts’ metabolism can exhaust the intestinal barrier resulting in serious effects on the health of the host.
Protracted immune deregulations can lead to severe disorders including diabetes, cancer and inflammatory bowel…
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