CORDIS Project
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This project focuses on creating a new delivery platform for allergy vaccines using microneedles and membrane fusion techniques. The goal is to enhance the efficacy and safety of allergen-specific immunotherapy, making it more patient-friendly and reducing the need for frequent injections.
In this project we aim to develop a new delivery platform for allergy vaccines with a high efficacy and a high safety profile combining membrane fusion-mediated delivery and microneedle-based dermal delivery.Background:
Within the ERC Starting Grant “Direct Drug Delivery”, I developed a method for the controlled fusion of liposomes with cells. A set of complementary peptide amphiphiles (coilK and coilE), able to form heterodimeric coiled coils, were shown to induce targeted and efficient fusion…
UNIVERSITEIT LEIDEN
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