CORDIS Project
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This project investigates how bacteria sense and regulate metal ions using specific proteins that control gene expression. By employing advanced spectroscopy techniques, the research aims to reveal the structural changes in these proteins when binding to metal ions, enhancing our understanding of microbial metal manage…
In this proposal, Dr.
Ruthstein and her new group at the chemistry department in Bar-Ilan University, Israel, will determine the sensing and transcription mechanisms of metal ion sensors in bacteria.
Metals are commonly found as natural constituents of proteins; however, many metal ions can be toxic when free in biological fluids.
Hence, microorganisms have evolved considerable regulatory machinery to control the intracellular and extracellular concentrations and types of metal ions encountered…
BAR ILAN UNIVERSITY
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