CORDIS Project
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This project investigates the development and activation of gamma delta T cells, which play a significant role in cancer immunity. By utilizing advanced techniques like single-cell RNA sequencing, the research aims to enhance understanding of T cell receptor signaling and its implications for immunotherapy.
T cells are key constituents of our immune system.
Two types of T cells are conserved evolutionary and across species: αβ and γδ T cells.
While αβ T cells have been intensively studied during the last decades, our knowledge on the development and activation of γδ T cells is still limited.
Recently, γδ T cells have become increasingly attractive for immunotherapy of cancer due to efficient killing of tumour cells independently of major histocompatibility complex (MHC) antigen presentation.
The pr…
INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES
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