CORDIS Project
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This project explores the relationship between genetic variations and observable traits by studying a specific protein complex involved in inflammation. By utilizing advanced techniques in mass spectrometry and imaging, it aims to clarify how changes at the molecular level can lead to different biological outcomes.
One of key challenges in current biology is to characterize the genotype to phenotype transition and explain how genomic variation results in specific phenotypes.
According to the 'modular biology' paradigm, dynamically regulated multi-protein modules mediate this transition.
My project aims at testing this paradigm by applying to a clinically highly relevant case study an integrated workflow of new technologies developed in the host laboratory.
In particular, I will focus on a novel ubiquitin…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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