CORDIS Project
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This project investigates how long-term exposure to medical drugs affects the evolution of the human gut microbiome. It focuses on the relationship between drug-induced microbial changes, metabolism, and antibiotic resistance, utilizing mouse models to explore these interactions at a molecular level.
The human gastrointestinal tract harbors trillions of microbes, known as the gut microbiota.
This microbial community helps modulating developmental, immunological, and metabolic functions of the human host and it plays an important role in medicinal drug response.
Several works showed the bidirectional relationship between the gut microbiota and drugs.
Medication modifies microbiome composition both in vitro and in the human gut.
Further, commonly used drugs influence the microbiome metabolic f…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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