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The DiSrupT RR-TB trial evaluates a new approach for managing rifampicin-resistant tuberculosis using whole genome sequencing directly on sputum samples. By integrating advanced sequencing technology and automated analysis, the project aims to enhance treatment precision and reduce transmission in high-burden areas lik…
The DiSrupT RR-TB pragmatic cluster randomized trial (CRT) will tackle the ongoing public health threat of rifampicin-resistant tuberculosis (RR-TB) and prevent the emergence of bedaquiline-resistant tuberculosis (BDQR-TB) as a new public health crisis.
The trial aims to evaluate an innovative all-in-1 solution for whole genome sequencing (WGS): the recently launched QIAseq xHYB Mtb assay for WGS directly on sputum (dWGS) in combination with Illumina sequencing and the novel digital MAGMA-MICK…
UNIVERSITEIT ANTWERPEN
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