CORDIS Project
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This project investigates the role of transglutaminase-2 in diabetes-related sexual dysfunction and fibrosis. By exploring the enzyme's impact on vascular function and fibrosis, it aims to identify new therapeutic targets for improving sexual health in individuals affected by diabetes.
Diabetes impairs blood supply and disrupts the integrity of the nervous system in genital organs, leading to sexual dysfunction (SD) and genital tissue fibrosis in both sexes. SD is strongly correlated with depression, reduced social well-being, and a diminished quality of life.
Current therapeutic options for SD are inadequate, have important side effects, and no effective treatments exist for vaginal/penile fibrosis, underscoring an urgent need for advanced mechanistic studies to identify new…
AARHUS UNIVERSITET
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