CORDIS Project
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This project investigates the genetic and epigenetic factors contributing to obesity and its phenotypic variation. By studying isogenic mice, it aims to uncover the molecular mechanisms that influence body weight and disease susceptibility, providing valuable insights for obesity research.
Current estimates place the prevalence of obesity beyond 1 billion by the year 2030.
As a critical risk factor for heart disease, diabetes and stroke, obesity represents one of the chief socio-economic challenges of our day.
While studies have mapped a genetic framework for understanding obesity, the etiological contribution of several regulatory layers, and in particular epigenetic regulation, remain poorly understood. A perfect example, we know that isogenic C57Bl6/J mice can vary by as much a…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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