CORDIS Project
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This research investigates the role of the histone demethylase LSD1 in gene transcription and chromatin organization using the fruit fly model. The project aims to uncover LSD1's specific functions and interactions, which may have implications for cancer treatment.
Each cell within an organism contains the same genetic information, however, only a specific subset of genes is transcribed in a given cell at a given time.
This cell/stage specific transcription is controlled by the coordinated action of signaling pathways, chromatin associated proteins and transcription factors.
Defects in chromatin organization and gene expression due to aberrant activity of chromatin modifying enzymes can contribute to diseases such as cancer.
Since its discovery, the histon…
UNIVERSITE TOULOUSE III - Paul Sabatier
UNIVERSITE PAUL SABATIER TOULOUSE III
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