CORDIS Project
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This project focuses on developing a human skin model to study Staphylococcus aureus infections and vaccine development. It integrates immune components to better understand the pathogen's mechanisms and provides alternatives to animal testing.
Staphylococcus aureus (S. aureus) is a major human pathogen and cutaneous infections are among the leading cause of emergency department visits.
Unfortunately, S. aureus vaccine development is hindered by the lack of known correlates of protection.
Three dimensional organotypic human skin models may represent a valid alternative to animal infection model.Indeed, S. aureus expresses several human-specific virulence factors.
However, at the present such models have been rarely used in the S. aureu…
GLAXOSMITHKLINE VACCINES SRL
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Netherlands, Utrecht
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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