CORDIS Project
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This project develops advanced mass spectrometry techniques to study how small molecules influence nucleic acid structures. By integrating various scientific disciplines, it aims to reveal the mechanisms behind ligand-induced changes in nucleic acids, which are crucial for understanding cell regulation and drug interac…
50 years after the discovery of the DNA double helix, the variety of structures that nucleic acids can adopt continues to surprise the scientific community.
Specific structures and conformational changes are linked to important functions in cell regulation.
Understanding the principles that govern how small molecules such as natural metabolites or synthetic drugs modulate the nucleic acid structures is of prime importance for molecular biology and pharmacology.
The field however suffers from the…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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