CORDIS Project
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This project focuses on developing a novel inhibitor for the OGG1 enzyme to treat Idiopathic Pulmonary Fibrosis (IPF). By reducing inflammation and fibrosis in the lungs, the compound aims to improve patient outcomes and survival rates in this severe condition.
Fibrosis in response to tissue damage or persistent inflammation is a pathological hallmark of many chronic degenerative diseases whereIdiopathic Pulmonary Fibrosis (IPF) is one of the most severe diseases. IPF is a progressive condition with unknown etiology and a mediansurvival of three years from diagnosis.
Current medical treatment is limited to slowing down the disease and thus there is still a high unmet medical need. OGG1 enzyme has a major role in DNA repair in conditions of oxidative st…
KAROLINSKA INSTITUTET
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