CORDIS Project
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This project develops a microfluidic platform called DOMES to create advanced 3D cell culture models for studying congenital anomalies, particularly in kidney development. It aims to understand how environmental factors influence organ formation through precise control of stem cell behavior in vitro.
In Europe, 263 per 10,000 pregnancies are diagnosed with a fetal congenital anomaly.
Congenital anomalies, also referred to as birth defects, are defined as structural or functional disorders that occur during fetal development and are inherited, and/or caused by environmental factors.
Unfortunately, the link between environmental factors, such as drugs, toxins or other chemicals, and the manifestation of these multifactorial disorders is poorly understood.
To identify environmental factors affe…
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