CORDIS Project
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This project aims to develop new anticancer drugs using N-heterocyclic carbenes, gold, and selenium. By synthesizing and testing these compounds, it seeks to create targeted therapies that are more effective and less toxic than current chemotherapy options.
This project aims to design new anticancer drugs by using N-heterocyclic carbenes (NHC), gold (Au), and selenium (Se), which have not been explored before. NHCs are chosen as key ligands in homogeneous catalysis with transition metals.
Gold compounds, like auranofin, disrupt tumor growth by inhibiting key enzymes.
Se triggers cancer cell death by inducing oxidative stress and blocking sulfur-based cell components.
Cancer poses a global threat, causing millions of deaths and huge economic losses,…
UNIVERSITEIT GENT
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