CORDIS Project
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This project aims to develop methods for inhibiting enzyme activity by modulating protein-protein interactions. By utilizing diversity-oriented synthesis, it seeks to discover new chemical compounds that can effectively target enzyme regulation, potentially transforming drug discovery and expanding tools for chemical b…
This proposal aims to exploit diversity-oriented synthesis in order to lay the scientific and technological foundations for the development of enzyme inhibition by protein-protein interaction (PPI) modulation as a tool for chemical biology and molecular therapeutics.
We will deploy diversity-oriented synthesis lead discovery to explore concepts for PPI modulation in important enzyme families.
This work will yield new chemical entities with a spectrum of properties directed against candidate macr…
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