CORDIS Project
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This project studies the role of the immune environment in the early stages of myelodysplastic syndromes, a type of blood cancer. It aims to identify how immune dysfunction contributes to disease progression and explore new therapeutic strategies to prevent or treat the condition.
Myelodysplastic syndromes (MDS) are heterogeneous clonal hematopoietic stem-cell malignancies of the elderly. MDS remain uncurable by existing pharmacological therapies, aimed at eradicating mutant clones.
Clonal cytopenias of undetermined significance (CCUS) occur in elderly patients harboring MDS-driver mutations in their bone marrow cells and almost always preclude MDS, representing an optimal setting for studying the mechanisms driving the onset of MDS.
In a preliminary study, I discovered t…
FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA
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