CORDIS Project
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The project investigates the hormonal disorder polycystic ovary syndrome (PCOS) by studying cell communication in the neuroendocrine-adipose tissue-ovary axis. It aims to develop new animal models to better understand PCOS pathogenesis and identify potential therapies.
Polycystic ovary syndrome (PCOS) is a human hormonal disorder of complex etiology, characterized by reproductive, endocrine and metabolic abnormalities, which affects 15% of women of reproductive age and has a very low survival rate.
Recent studies on its pathophysiology suggest that it reflects alterations in homeostatic feedback mechanisms between the ovaries, adipose tissue, and hypothalamic circuits that develop during embryogenesis.
Despite its high prevalence and significant impact on heal…
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