CORDIS Project
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This project investigates the role of solute carrier transporters in the uptake of various approved drugs. By examining human cell lines with specific transporter deletions, the research aims to clarify how these proteins influence drug efficacy and safety.
The transport of nutrients and metabolites across lipid membranes is a critical and essential biological process in both normal and pathological conditions.
Specialized integral membrane proteins known as transporters are responsible for the movement of virtually any known class of biologically active molecules across membranes.
Perhaps not surprisingly, there is increasing evidence that many drugs in clinical use also employ carried-mediated transport as the predominant entry method into the ce…
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