CORDIS Project
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DrugSynergy aims to enhance drug combination strategies using a systems biology approach. The project focuses on optimizing interactions between drugs to improve efficacy and reduce toxicity in treating chronic diseases.
The complex physiopathology of human chronic diseases includes networks robustness, feedback loops, and cross-talks, which may induce limited efficacy, resistance, and/or excessive toxicity of an individual drug.
Learning how to combine drugs in order to improve treatment efficacy and lower undesired toxicity is a major biomedical challenge.
Current strategies for drug repositioning and optimization of drug combinations have two man limitations: 1) they mostly use public data and databases, whic…
INSTITUT CURIE
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