CORDIS Project
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The project focuses on developing targeted therapies for desmoplastic small round cell tumor (DSRCT), a rare and aggressive cancer. It combines research on molecular mechanisms with innovative immunotherapy approaches to improve treatment outcomes for affected patients.
Desmoplastic small round cell tumor (DSRCT) is an aggressive rare sarcoma that occurs in adolescents and young adults. DSRCT has a dismal prognosis: despite aggressive therapy, 3-year overall survival has been estimated at 44% and the 5-year survival rate remains around 15%.
Current therapeutic approaches, including chemotherapy (remain highly toxic) and surgery, are yet to achieve complete disease control.
The development of safe and efficient molecularly targeted-therapies, as well as a compre…
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