CORDIS Project
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This project focuses on developing new cancer therapies by designing multi-target agents that inhibit three key enzymes involved in tumor progression: HDAC1, CK2, and MMP2. The approach aims to overcome resistance issues associated with traditional single-target drug therapies.
Traditional drug design strategy based on a single target has serious difficulties in developing new therapies for diseases such as cancer.Cancer is a very complex multi-genetic disease that involves multiple crosstalks between signaling networks.
The use of cocktails of various anticancer agents interfering with different mechanisms has been the standard treatment to prevent the problems of resistance.An alternative approach is to design multi-target modulators, directed to different disease me…
FUNDACION UNIVERSITARIA SAN PABLO-CEU
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