CORDIS Project
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This project focuses on understanding the role of deubiquitylases in cellular signaling networks. By employing advanced proteomic techniques, it aims to systematically decode how these enzymes regulate protein functions and stability, which is crucial for comprehending various biological processes and diseases.
Cellular processes are largely governed by sophisticated protein posttranslational modification (PTM)-dependent signaling networks, and a systematic understanding of regulatory PTM-based networks is a key goal in modern biology.
Ubiquitin is a small, evolutionarily conserved signaling protein that acts as a PTM after being covalently conjugated to other proteins.
Reversible ubiquitylation forms the most versatile and largest eukaryote-exclusive signaling system, and regulates the stability and f…
KOBENHAVNS UNIVERSITET
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