CORDIS Project
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This project explores innovative methods for synthesizing quaternary alpha-amino acids using the chirality of tertiary alpha-amino acids. It aims to extend these methodologies to create biologically active compounds and new chiral ligands for asymmetric catalysis.
A few years ago, the host laboratory has started a new project based on Memory of Chirality and dynamic axial chirality of tertiary aromatic amides and developed a new asymmetric synthesis of quaternary alpha-amino acids by using only the chirality of starting tertiary alpha-amino acid.
The host laboratory is also currently working on the development of a new synthesis of enantioenriched non proteinogenic tertiary alpha-amino acid starting from achiral compounds (glycine and aromatic acid) and b…
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