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The DYNAMITE project investigates the molecular processes involved in the initiation and early elongation of mitochondrial translation. By utilizing advanced techniques, it aims to create a detailed model of how mitochondria produce energy, which could inform the development of safer drugs and therapies for mitochondri…
The DYNAMITE project aims to uncover the precise sequence of molecular events that govern human mitochondrial translation initiation and its transition to elongation.
Mitochondria are essential for energy production, and defects in their translation machinery cause severe diseases and contribute to drug toxicity.
Despite recent structural advances, the dynamic steps of initiation remain poorly understood.To address this gap, DYNAMITE will combine kinetic assays using stopped-flow fluorescence to…
KAROLINSKA INSTITUTET
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United Kingdom, Leeds
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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