CORDIS Project
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This research project investigates the mechanisms of homologous recombination, a crucial process for DNA repair and genome stability. By using single molecule analysis, it aims to understand the dynamics of recombinase proteins and their interactions with DNA, which is vital for developing cancer treatments that target…
The goal of the research is to understand the mechanisms and biological function of complex genome transactions such as homologous recombination.
Homologous recombination, the exchange of sequences between homologous DNA molecules, is essential for accurate genome duplication, DNA damage repair and chromosome segregation.
Single molecule analysis provides information on intermediate states, functional and structural variability and the distribution of variable states that cannot be recovered fro…
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
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