CORDIS Project
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This project investigates the mechanisms of genome processing, focusing on how proteins interact during DNA transcription and replication. By studying the dynamics of these processes, the research aims to understand the factors that cause stalling in these critical biological functions.
The vast quantity of information in our genomes must continuously be read out and processed.
This is done by proteins, acting either individually or as part of larger protein complexes.
How this genome processing operates successfully, given the crowded nature of the DNA track as well as its mechanical constraints and coiling, is a question of fundamental interest.We will investigate the dynamics of genome processing during DNA transcription and replication.
Throughout, we ask the question, wha…
TECHNISCHE UNIVERSITEIT DELFT
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