CORDIS Project
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The ypha System project addresses inefficiencies in drug development by enhancing cell culture methods. It introduces a Fluidic Adaptor that allows for controlled fluid exchange in standard well plates, improving the relevance of cell culture models for drug testing.
The current preclinical drug development pipeline is highly inefficient with 9 out of 10 drugs failing when first tested in humans.
Of those failures, between 69% and 81% is due to a lack of efficacy (52-57%) or safety (17-24%), indicating that the predictivity of currently used cell culture and animal models is not high enough.
While promising human cell culture models have arisen in the last decades (e.g. pluripotent stem cell models, spheroids, organoids), the environment of these models is t…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
DEMCON LIFE SCIENCES & HEALTH ENSCHEDE BV
Netherlands, Enschede
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
Germany, SATERLAND
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
OSPEDALE PEDIATRICO BAMBINO GESU
Italy, Roma
Type: Research institute
Activity type: Research Organisations
SME: No
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