CORDIS Project
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This project develops innovative technologies to control protein signaling in specific neuron subpopulations using light. By studying protein dynamics in active brain circuits during learning tasks in mice, the research aims to enhance understanding of multi-cellular behavior and inform new treatments for brain disorde…
Protein signaling in cells is precisely coordinated in space and time.
Molecular chemogenetics, optogenetics, and biosensors have generated a scientific revolution enabling the spatiotemporal codes of protein signaling in single cells.
However, it is a great challenge to study protein dynamics in a physiological multicellular environment due to the extensive variability in protein signaling within individual cells, as well as the sparsity of driver cells responsible for a specific physiological…
KAROLINSKA INSTITUTET
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